The human papillomavirus (HPV) vaccine, which can also guard against oral, throat and anal cancers, will be offered to boys aged 12 to 13 in England, public health minister Steve Brine said.
Experts and campaigners have been calling for equal access to the jab, which is already routinely offered to girls of the same age at secondary school and is free up until they turn 18.
The announcement follows a recommendation from the Joint Committee on Vaccination and Immunisation (JCVI), which said last week that a “gender-neutral” programme to protect against the sexually transmitted infection would be “cost-effective”.
Mr Brine said “Any vaccination programme must be firmly grounded in evidence to ensure that we can get the best outcomes for patients, but as a father to a son, I understand the relief that this will bring to parents.”
Dr Mary Ramsay, head of immunisations at Public Health England (PHE), said: “I’m pleased that adolescent boys will be offered the HPV vaccine.
“Almost all women under 25 have had the HPV vaccine and we’re confident that we will see a similarly high uptake in boys.”
The announcement follows similar decisions by the Welsh and Scottish governments after the JCVI recommendation.
Read more about the HPV vaccine HPV vaccination to be introduced for all teenage boys in UK, government announces
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